Stress Hyperglycemia, Inflammation, and Cardiovascular Events

Oxidative Stress and Inflammation in Cardiovascular Disease

Blood clotting, inflammation, and thrombosis in cardiovascular events: perspectives.

Worldwide, cardiovascular disease (CVD) is a leading cause of death. Endothelial dysfunction is now recognized to be a key platform for the pathophysiological effects of atherosclerosis. It is now well accepted that atherosclerosis is not merely a benign and passive process, but is in fact a dynamic and progressive disease arising from a combination of endothelial damage/dysfunction, inflammati...

Stress Hyperglycemia

Injury and destruction of the islets precede the onset of clinical hyperglycemia in Type 1 diabetes mellitus (DM). This represents the activation of an autoimmune state followed by an imbalance between T-helper and T-suppressor cells and the susceptibility or resistance of the β-cells to injury. Because some stress hormones (particularly cortisol) are known to modulate the immune system and oth...

Postprandial Hyperglycemia and Cardiovascular Disease

In the recent HEART2D (Hyperglycemia and its Effect After Acute Myocardial Infarction on Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus) study, published in this issue of Diabetes Care, Raz et al. (1) try to answer a hotly debated question of the last 10 years: is postprandial hyperglycemia an independent risk factor for cardiovascular disease in diabetes? This question, high...

P126: Post-Traumatic Stress Disorder and Inflammation

Post traumatic stress disorder, a special disease that also accompanies with histological changes such as inflammation. In this paper we decided to review the relation between PTSD and inflammation. Stressful events causes immune system dysfunction by suppressing natural killer cells and altering levels of cytokines. Also in this condition, cytotoxic T lymphocytes results in under strained pro-...